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To continue with the example of drug testing, a control is a group that has not been administered the drug of interest. This group receives either no preparation at all or a sham preparation and we would say that the control group should show a negative or null effect. In other examples, outcomes might be measured as lengths, times, percentages, in the drug testing example, we could measure the percentage of patients cured. In this case, the treatment is inferred to have no effect when the treatment group, some improvement is expected in the placebo group due to the placebo effect, and this result sets the baseline which the treatment must improve upon.

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